| 7,8-didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol; 7,8-didehydro-4,5-epoxy-17-methyl-(5α,6α)-morphinan-3,6-diol; λ-morphine; morphine | |
| Links: | 🌍 Wikipedia, 📏 NIST, 🕷 ChemSpider, 📖 PubMed, 📖Houben-Weyl, 2. Band (Morphin); p. 425, 852, |
| MeSH: | Analgesics; Analgesics, Opioid; Central Nervous System Agents; Narcotics; Sensory System Agents |
| CAS RN: | [57-27-2] |
| Formula: | C17H19NO3; 285.34 g/mol |
| InChiKey: | BQJCRHHNABKAKU-KBQPJGBKSA-N |
| SMILES: | CN1CC[C@]23[C@H]4Oc5c(O)ccc(C[C@@H]1[C@@H]2C=C[C@@H]4O)c35 |
| Pharmaceutical use: | analgesic; euphoric; stimulant |
| Toxicology (LD50): | 61.0 mg/Kg (cat, sc); 210 mg/Kg(dog, sc); 700 mg/Kg(frog, sc); 540 mg/Kg(guinea~pig, sc); 272 mg/Kg(mouse, iv); 531 mg/Kg(mouse, sc); 700 mg/Kg(mouse, sc); 150 mg/Kg(rabbit, ip); 500 mg/Kg(rabbit, ip); 266 mg/Kg(rabbit, sc); 500 mg/Kg(rabbit, sc); 400 mg/Kg(rat, sc) |
| Melting point: | 255 °C |
| Log10 partition octanol / water: | 0.76 |
| 1g dissolves in: 2.51g piperidine; 6.25g diethyl ether; 13.50g diethylamine; 16.39g aniline; 113.51g pentanol; 166.67g ethanol; 222.22g 1,2,3-propanetriol; 537.35g ethyl acetate; 781.25g 2-propanone; 1,170.96g hexane; 1,526.72g trichloromethane; 1,600.00g benzene; 1,984.13g trichloromethane; 3,472.22g water; 3,533.57g water; 3,937.01g water; 4,464.29g diethyl ether; 6,410.26g tetrachloromethane | |